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Glycogen Synthase 抗体 (pSer641)

This anti-Glycogen Synthase antibody is a 兔 多克隆 antibody detecting Glycogen Synthase in WB, IP, EIA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN303100
发货至: 中国

Quick Overview for Glycogen Synthase 抗体 (pSer641) (ABIN303100)

抗原

See all Glycogen Synthase (GYS) 抗体
Glycogen Synthase (GYS)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Glycogen Synthase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer641

    特异性

    This antibody is specific for the phosphorylated form of GS at S640. Phosphorylation of GS at S640 has been associated with Antiphospholipid Antibody Syndrome.

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Human Muscle Glycogen Synthase phospho peptide corresponding to a region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
  • 应用备注

    Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot. Immunoprecipitation. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preserevative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    Glycogen Synthase (GYS)

    别名

    Glycogen Synthase

    背景

    Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephos-phorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3b that mainly functions to phos-phorylate muscle glycogen synthase.Synonyms: GYS, GYS1, muscle Glycogen Synthase

    基因ID

    2997

    NCBI登录号

    NP_001155059

    UniProt

    P13807
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