Glycogen Synthase 抗体 (pSer641)
Quick Overview for Glycogen Synthase 抗体 (pSer641) (ABIN303100)
抗原
See all Glycogen Synthase (GYS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer641
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特异性
- This antibody is specific for the phosphorylated form of GS at S640. Phosphorylation of GS at S640 has been associated with Antiphospholipid Antibody Syndrome.
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Human Muscle Glycogen Synthase phospho peptide corresponding to a region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
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应用备注
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Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot. Immunoprecipitation. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preserevative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Glycogen Synthase (GYS)
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别名
- Glycogen Synthase
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背景
- Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephos-phorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3b that mainly functions to phos-phorylate muscle glycogen synthase.Synonyms: GYS, GYS1, muscle Glycogen Synthase
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基因ID
- 2997
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NCBI登录号
- NP_001155059
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UniProt
- P13807
抗原
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