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FOXO1 抗体 (AA 456-655)

FOXO1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030989
发货至: 中国
  • 抗原 See all FOXO1 抗体
    FOXO1 (Forkhead Box O1 (FOXO1))
    抗原表位
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    AA 456-655
    适用
    • 233
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    人, 大鼠
    宿主
    • 212
    • 24
    • 1
    克隆类型
    • 205
    • 32
    多克隆
    标记
    • 109
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    This FOXO1 antibody is un-conjugated
    应用范围
    • 192
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    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Human partial recombinant protein (AA 456-655) was used as the immunogen for this FOXO1 antibody.
    亚型
    IgG
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  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the FOXO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the FOXO1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    FOXO1 (Forkhead Box O1 (FOXO1))
    别名
    FOXO1 (FOXO1 产品)
    背景
    Forkhead box protein O1, also known as FKHR or FOXO1A, is a protein that in humans is encoded by the FOXO1 gene. It is mapped to 13q14.11. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO1 plays important roles in regulation of gluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadipocyte to commit to adipogenesis. This gene is primarily regulated through phosphorylation on multiple residues. Its transcriptional activity is dependent on its phosphorylation state. Additionally, FOXO1 may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
    基因ID
    2308
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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