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FOXO1 抗体 (AA 456-655)

This anti-FOXO1 antibody is a 兔 多克隆 antibody detecting FOXO1 in WB. Suitable for 人 和 大鼠.
产品编号 ABIN3030989
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FOXO1 抗体 (AA 456-655) (ABIN3030989)

抗原

See all FOXO1 抗体
FOXO1 (Forkhead Box O1 (FOXO1))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This FOXO1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 456-655

    纯化方法

    Antigen affinity

    免疫原

    Human partial recombinant protein (AA 456-655) was used as the immunogen for this FOXO1 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the FOXO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the FOXO1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    FOXO1 (Forkhead Box O1 (FOXO1))

    别名

    FOXO1

    背景

    Forkhead box protein O1, also known as FKHR or FOXO1A, is a protein that in humans is encoded by the FOXO1 gene. It is mapped to 13q14.11. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO1 plays important roles in regulation of gluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadipocyte to commit to adipogenesis. This gene is primarily regulated through phosphorylation on multiple residues. Its transcriptional activity is dependent on its phosphorylation state. Additionally, FOXO1 may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

    基因ID

    2308

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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