FOSB 抗体 (N-Term)
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Quick Overview for FOSB 抗体 (N-Term) (ABIN3030918)
抗原
See all FOSB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the N-terminus of human FosB (MFQAFPGDYDSGSRC) was used as the immunogen for this FosB antibody (100% homologous in human, mouse and rat).
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the FosB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the FosB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))
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别名
- FosB
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背景
- FBJ murine osteosarcoma viral oncogene homolog B is a protein that in humans is encoded by the FOSB gene. It is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Delta FOSB is a truncated splice variant of FOSB. It has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. It also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.
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UniProt
- P53539
抗原
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