Cullin 3 抗体
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Quick Overview for Cullin 3 抗体 (ABIN303084)
抗原
See all Cullin 3 (CUL3) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to amino acids 1-12 of Cul3 (N-terminus) coupled to KLH.
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纯化方法
- Delipidation and defibrination
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免疫原
- Synthetic peptide
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anti-Cullin 3 (CUL3) antibody
CUL3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cullin 3 (CUL3) (AA 411-510) antibodyCUL3 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cullin 3 (CUL3) antibodyCUL3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cullin 3 (CUL3) (AA 569-768) antibodyCUL3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 3 (CUL3) antibodyCUL3 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB1560 unconjugated Recombinant Antibody
anti-Cullin 3 (CUL3) (AA 650-700) antibodyCUL3 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Cullin 3 (CUL3) (AA 301-400) antibodyCUL3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-Cullin 3 (CUL3) (AA 650-700) antibodyCUL3 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 3 (CUL3) antibodyCUL3 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 7B6 unconjugated Recombinant Antibody
anti-Cullin 3 (CUL3) (AA 618-667) antibodyCUL3 适用: 人, 斑马鱼, Cow, 小鸡, 犬, 豚鼠, 马, 兔, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunoprecipitation. Immunohistochemistry on paraffin sections: 1: 500. Western Blot: 1: 500 - 1: 1000. ELISA: 1: 2000 - 1: 10000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- Cullin 3 (CUL3)
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别名
- Cullin-3
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背景
- Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 3 is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cul3 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul3 may also contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Unlike Cul1 and Cul2, Cul3 seems not to be a part of the SCF complex consisting of CUL1, RBX1, SKP1 and SKP2. Cul3 also interacts with RNF7 and is part of a complex with TIP120A/CAND1, Cyclin E and RBX1.Synonyms: CUL-3, CUL3, KIAA0617
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基因ID
- 8452
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NCBI登录号
- NP_003581
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UniProt
- Q13618
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途径
- M Phase
抗原
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