电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Cullin 3 抗体

CUL3 适用: 人, 小鼠 WB, IHC (p), IP, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN303084
发货至: 中国
  • 抗原 See all Cullin 3 (CUL3) 抗体
    Cullin 3 (CUL3)
    适用
    • 51
    • 22
    • 18
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 49
    • 1
    • 1
    克隆类型
    • 48
    • 3
    多克隆
    标记
    • 30
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cullin 3 antibody is un-conjugated
    应用范围
    • 23
    • 16
    • 13
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to amino acids 1-12 of Cul3 (N-terminus) coupled to KLH.
    纯化方法
    Delipidation and defibrination
    免疫原
    Synthetic peptide
    Top Product
    Discover our top product CUL3 Primary Antibody
  • 应用备注
    Immunoprecipitation. Immunohistochemistry on paraffin sections: 1: 500. Western Blot: 1: 500 - 1: 1000. ELISA: 1: 2000 - 1: 10000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    Cullin 3 (CUL3)
    别名
    Cullin-3 (CUL3 产品)
    别名
    CUL-3 antibody, Cullin-3 antibody, CUL-3-A antibody, Cullin-3-A antibody, cul3 antibody, cul3a antibody, CUL-3-B antibody, Cullin-3-B antibody, cul3b antibody, wu:fc37e01 antibody, CUL3 antibody, ATCUL3 antibody, ATCUL3A antibody, CUL3A antibody, T24P13.25 antibody, cullin 3 antibody, cullin 3A antibody, PHA2E antibody, AI467304 antibody, AW146203 antibody, mKIAA0617 antibody, cullin 3 antibody, cullin 3 L homeolog antibody, cullin 3 S homeolog antibody, cullin-3 antibody, Cullin-3 (CUL-3) antibody, cullin 3a antibody, CULlin antibody, CUL3 antibody, cul3 antibody, cul3.L antibody, cul3.S antibody, PTRG_11586 antibody, Smp_117580 antibody, cul3a antibody, Cul3 antibody, cul-3 antibody
    背景
    Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 3 is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cul3 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul3 may also contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Unlike Cul1 and Cul2, Cul3 seems not to be a part of the SCF complex consisting of CUL1, RBX1, SKP1 and SKP2. Cul3 also interacts with RNF7 and is part of a complex with TIP120A/CAND1, Cyclin E and RBX1.Synonyms: CUL-3, CUL3, KIAA0617
    基因ID
    8452
    NCBI登录号
    NP_003581
    UniProt
    Q13618
    途径
    M Phase
You are here:
客服