DAXX 抗体 (AA 325-341)
Quick Overview for DAXX 抗体 (AA 325-341) (ABIN3030705)
抗原
See all DAXX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 325-341
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 325-341 (QERRHLDLIYNFGCHLT) were used as the immunogen for this Daxx antibody (100% homologous in human, mouse and rat).
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亚型
- IgG
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anti-Death-Domain Associated Protein (DAXX) (AA 561-660) antibody
DAXX 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 558-740) antibodyDAXX 适用: 人 WB, ICC 宿主: 小鼠 Monoclonal DAXX-01 unconjugated
anti-Death-Domain Associated Protein (DAXX) antibodyDAXX 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 56-345) antibodyDAXX 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (C-Term) antibodyDAXX 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) antibodyDAXX 适用: 人 WB, IF, EIA 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Death-Domain Associated Protein (DAXX) (pSer213) antibodyDAXX 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (pSer495) antibodyDAXX 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 1-740) antibodyDAXX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 580-740) antibodyDAXX 适用: 人 WB, ICC, IP 宿主: 小鼠 Monoclonal DAXX-03 unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Daxx antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Daxx antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- DAXX (Death-Domain Associated Protein (DAXX))
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别名
- Daxx
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背景
- Death-domain associated protein, also known as DAP6 (Death-associated protein 6) or BING2, was first discovered through its cytoplasmic interaction with the classical death receptor Fas. The gene encodes a 740-amino acid polypeptide containing a nuclear localization signal. Functional analyses byYang et al.(1997) demonstrated that Daxx binds to the Fas death domain and enhances Fas-mediated apoptosis. The authors suggested that DAXX and FADD define 2 distinct apoptotic pathways downstream of Fas. The gene is mapped to human chromosome 6p21.3 by somatic cell hybrid panels and fluorescence in situ hybridization, a region containing the HLA and putative autoimmune disease genes. MSP58 overexpression relieved DAXX-mediated transcriptional repression. Immunoprecipitation and Western blot analysis with DAXX mutants showed that the N terminus of the protein interacts with the C terminus of DMAP. Transient expression of DAXX or DMAP1 caused repression of glucocorticoid receptor-mediated transcription.
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UniProt
- Q9UER7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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