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CDK5 抗体 (C-Term)

This anti-CDK5 antibody is a 兔 多克隆 antibody detecting CDK5 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3030615
发货至: 中国

Quick Overview for CDK5 抗体 (C-Term) (ABIN3030615)

抗原

See all CDK5 抗体
CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CDK5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of human Cdk5 (QRISAEEALQHPYFSDFCPP) was used as the immunogen for this Cdk5 antibody (100% homologous in human, mouse and rat).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Cdk5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Cdk5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

    别名

    Cdk5

    背景

    Cyclin-Dependent Kinase 5, is also know as PSSALRE. The p34(CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. Cdk5 expression is in all human tissues and cell lines tested. The the gene is mapped to chromosome 7q36. Cyclin-dependent kinase 5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. It is required for proper development of the mammalian central nervous system. To be activated, Cdk5 must associate with its regulatory subunit, p35(CDK5R1). It can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.

    UniProt

    Q00535

    途径

    Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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