Claudin 5 抗体 (AA 191-218)
Quick Overview for Claudin 5 抗体 (AA 191-218) (ABIN3030536)
抗原
See all Claudin 5 (CLDN5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 191-218
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 191-218 (RPDLSFPVKYSAPRRPTATGDYDKKNYV-human) were used as the immunogen for the Claudin-5 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Claudin 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Claudin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Claudin 5 (CLDN5)
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别名
- Claudin 5
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背景
- Claudin-5, also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80 % of VCFS patients. This gene encodes a member of the claudin family. Family members are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Additionally, it plays a major role in tight junction-specific obliteration of the intercellular space.
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基因ID
- 7122
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途径
- Hepatitis C
抗原
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