CXCR4 抗体 (AA 31-43)
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Quick Overview for CXCR4 抗体 (AA 31-43) (ABIN3030515)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-43
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 31-43 (EENANFNKIFLPT) were used as the immunogen for this CXCR4 antibody.
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亚型
- IgG
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应用备注
- Titration of the CXCR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the CXCR4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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别名
- CXCR4
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背景
- Chemokine,CXC Motif, Receptor 4, also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. By PCR analysis of human/hamster hybrid cell DNA, Herzog et al.(1993) showed that the NPY3R gene is located on human chromosome 2. Feng et al.(1996) showed that transient expression of the gene allowed nonhuman cells coexpressing recombinant CD4 to undergo Env-CD4-mediated cell fusion and productive HIV-1 infection. Peled et al.(1999) demonstrated that SDF1 and its receptor CXCR4 are critical for murine bone marrow engraftment by human SCID repopulating stem cells. Treatment of human cells with anti-CXCR antibodies prevented engraftment.
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UniProt
- P61073
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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