CBLC 抗体 (AA 444-458)
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- 抗原 See all CBLC 抗体
- CBLC (Cbl proto-oncogene C (CBLC))
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抗原表位
- AA 444-458
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBLC antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognizes RNF57/CBLC.
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Immunoaffinity Chromatography.
- 免疫原
- Synthetic peptide - KLH conjugated corresponding to amino acids 444-458 of Human Cbl-c.
- Top Product
- Discover our top product CBLC Primary Antibody
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anti-Cbl proto-oncogene C (CBLC) (AA 245-474) antibody
CBLC 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 444-458) antibodyCBLC 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 245-474) antibodyCBLC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 1-474) antibodyCBLC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 244-474) antibodyCBLC 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 3B4 unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 1-474) antibodyCBLC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 244-474) antibodyCBLC 适用: 人 WB 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 424-453), (C-Term) antibodyCBLC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0696 unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 1-30), (N-Term) antibodyCBLC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0694 unconjugated
anti-Cbl proto-oncogene C (CBLC) antibodyCBLC 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000-1/50000. Western Blot: 1/500-1/3000. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- CBLC (Cbl proto-oncogene C (CBLC))
- 别名
- CBLC / RNF57 (CBLC 产品)
- 别名
- CBL-3 antibody, CBL-SL antibody, RNF57 antibody, Cbl proto-oncogene C antibody, CBLC antibody, Cblc antibody
- 背景
- Cbl-c is also known as signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3, and RING finger protein 57. Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl-c (a.k.a. Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Cbl-c knock out mice show no obvious phenotype. Thus, the physiological role of Cbl-c is not known.Synonyms: CBL-3, CBL-C, CBL3, RING finger protein 57, SH3-binding protein CBL-C, Signal transduction protein CBL-C
- 基因ID
- 23624
- NCBI登录号
- NP_001124324
- UniProt
- Q9ULV8
- 途径
- EGFR Signaling Pathway
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