BOC 抗体 (AA 1002-1020)
Quick Overview for BOC 抗体 (AA 1002-1020) (ABIN3030172)
抗原
See all BOC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1002-1020
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 1002-1020 (DDSTHQLLQPQDCCHLQKQ-mouse) were used as the immunogen for this BOC antibody (100% rat homology).
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亚型
- IgG
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anti-Brother Of CDO (BOC) (AA 1-125) antibody
BOC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Brother Of CDO (BOC) (AA 668-866) antibodyBOC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Brother Of CDO (BOC) (AA 451-550) antibodyBOC 适用: 大鼠 ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Brother Of CDO (BOC) antibodyBOC 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Brother Of CDO (BOC) (Internal Region) antibodyVerified BOC 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Brother Of CDO (BOC) antibodyBOC 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the BOC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the BOC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- BOC (Brother Of CDO (BOC))
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别名
- BOC
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背景
- Brother Of CDO, also known as 'Brother of CDON' and BOC are cell surface receptors of the immunoglobulin(Ig)/fibronectin type III repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail. The domain structure of BOC is similar to that of CDON, and the proteins share 38 to 80 % amino acid identity in the individual extracellular domains. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 3. In contrast with CDON, the intracellular region of BOC was not essential for its ability to positively regulate differentiation. BOC is dependent on CDON for activity and that CDON/BOC complexes function to regulate myogenic differentiation. Wegorzewska et al.(2003) proposed that CDO and BOC play a role in the inverse relationship between differentiation and transformation of cells in the skeletal muscle lineage. The protein is expressed by commissural neurons, and targeted disruption of it in mouse resulted in the misguidance of commissural axons toward the floor plate.
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UniProt
- Q6AZB0
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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