Liver Arginase 抗体 (AA 307-323)
Quick Overview for Liver Arginase 抗体 (AA 307-323) (ABIN3030018)
抗原
See all Liver Arginase (ARG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 307-323
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 307-323 (KREGNHKPETDYLKPPK-rat) were used as the immunogen for this Arginase 1 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Arginase 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Arginase 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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别名
- Arginase 1
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背景
- Arginase is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. The isoform encoded by ARG1, referred to as the liver, or A-I, isoform, contributes 98 % of the arginase activity in liver but is also present in red cells. Using a rat ARG1 cDNA clone to probe a human liver cDNA library, Haraguchi et al.(1987) isolated and characterized a cDNA corresponding to the gene. By immunologic studies, 90 % of the arginase in red blood cells and liver was precipitated by an Arginase 1 antibody, whereas only 50 % of the arginase in kidney, brain, and the gastrointestinal tract reacted with it. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P07824
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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