APOE 抗体 (AA 19-317)
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Quick Overview for APOE 抗体 (AA 19-317) (ABIN3029996)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-317
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 19-317) was used as the immunogen for this ApoE antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA (Capture, recombinant human protein): 0.1-0.5 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the ApoE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- APOE (Apolipoprotein E (APOE))
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别名
- ApoE
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背景
- Apolipoprotein E, also known as AD2 or LPG, is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in ApoE result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple ApoE transcript variants.
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基因ID
- 348
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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