Annexin a1 抗体 (AA 2-346)
Quick Overview for Annexin a1 抗体 (AA 2-346) (ABIN3029968)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-346
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 2-346) was used as the immunogen for this Annexin A1 antibody.
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亚型
- IgG
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anti-Annexin A1 (ANXA1) (AA 6-346) antibody
ANXA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal ANXA1-3566 unconjugated
anti-Annexin A1 (ANXA1) (AA 144-248) antibodyANXA1 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (C-Term) antibodyVerified ANXA1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 IHC, FACS, StM 宿主: 小鼠 Monoclonal ANXA1-1671 unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Annexin A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Annexin A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- Annexin A1
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背景
- ANXA1, also known as Lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. It belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.
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基因ID
- 301
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途径
- Hormone Transport
抗原
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