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ADRA2A 抗体 (Middle Region)

ADRA2A 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029881
发货至: 中国
  • 抗原 See all ADRA2A 抗体
    ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))
    抗原表位
    • 15
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 39
    • 35
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 56
    • 1
    克隆类型
    • 57
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADRA2A antibody is un-conjugated
    应用范围
    • 33
    • 16
    • 13
    • 13
    • 12
    • 9
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human alpha 2a Adrenergic Receptor (ILVYVRIYQIAKRRTR) was used as the immunogen for this alpha 2a Adrenergic Receptor antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product ADRA2A Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Alpha 2a Adrenergic Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Alpha 2a Adrenergic Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))
    别名
    alpha 2a Adrenergic Receptor (ADRA2A 产品)
    别名
    ADRA2A antibody, AW122659 antibody, Adra-2 antibody, Adra-2a antibody, alpha(2A)AR antibody, alpha2-C10 antibody, alpha2A antibody, alpha2A-AR antibody, ADRA2 antibody, ADRA2R antibody, ADRAR antibody, ALPHA2AAR antibody, ZNF32 antibody, CA2-47 antibody, RATRG20 antibody, RG20 antibody, PORA2AR antibody, adrenoceptor alpha 2A antibody, alpha-2A adrenergic receptor-like antibody, adrenergic receptor, alpha 2a antibody, adra2a antibody, ADRA2A antibody, LOC100414445 antibody, Adra2a antibody
    背景
    The alpha 2A adrenergic receptor is a member of the G protein-coupled receptor superfamily which include three highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. Alpha2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
    UniProt
    P08913
    途径
    EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity
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