AFT1 抗体 (AA 1-271)
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Quick Overview for AFT1 抗体 (AA 1-271) (ABIN3029843)
抗原
See all AFT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-271
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 1-271) was used as the immunogen for this ATF1 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting points. Titration of the ATF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the ATF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- AFT1 (Activating Transcription Factor 1 (AFT1))
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别名
- ATF1
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背景
- Activating transcription factor 1 is a protein that in humans is encoded by the ATF1 gene. This gene encodes an activating transcription factor which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. It is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.
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基因ID
- 466
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
抗原
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