PIK3R1 抗体 (AA 447-461)
Our Local Distributor
北京 101111
Quick Overview for PIK3R1 抗体 (AA 447-461) (ABIN3029749)
抗原
See all PIK3R1 (PI3K p85a) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 447-461
-
纯化方法
- Antigen affinity
-
免疫原
- Amino acids 447-461 (KVYHQQYQDKSREYD-beta specific) was used as the immunogen for this PI3K antibody (100% human, mouse and rat homology).
-
亚型
- IgG
-
-
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr607) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-454) antibodyPI3K p85a 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibodyPI3K p85a 适用: 人, 小鼠 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6G10 unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 501-600) antibodyPI3K p85a 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-30), (N-Term) antibodyPI3K p85a 适用: 人, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB11634 unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibodyPI3K p85a 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr607) antibodyPI3K p85a 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (C-Term) antibodyPI3K p85a 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibodyKD Validated PI3K p85a 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2155 unconjugated Recombinant Antibody
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibodyPI3K p85a 适用: 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 3B7 unconjugated
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the PI3K antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the PI3K antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
-
别名
- PI3K
-
背景
- Phosphatidylinositol 3-kinase regulatory subunit 2, also called p85-Beta, PIK3R2 and PIK3, is an enzyme that in humans is encoded by the PIK3R2 gene. The NS1 protein from various influenza strains bind p85-beta, but not p85-alpha. Binding of p85-beta and activation of PI3K required tyr89 of NS1, and mutant viruses expressing NS1 with a tyr89-to-phe substitution grew more slowly in cell culture than wildtype viruses. Using mouse embryonic fibroblasts, Park et al. showed that, in addition to regulating PI3K function, p85-alpha/beta regulated the function of Xbp1s, a transcription factor that orchestrates the unfolded protein response (UPR) following endoplasmic reticulum (ER) stress. Overexpression of the protein in livers of ob/ob mice increased glucose tolerance and reduced blood glucose concentrations.
-
UniProt
- O00459
-
途径
- TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect
抗原
-
