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Tumor Protein p73 抗体 (AA 1-198)

This anti-Tumor Protein p73 antibody is a 兔 多克隆 antibody detecting Tumor Protein p73 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3029401
发货至: 中国

Quick Overview for Tumor Protein p73 抗体 (AA 1-198) (ABIN3029401)

抗原

See all Tumor Protein p73 (TP73) 抗体
Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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  • 28
多克隆

标记

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This Tumor Protein p73 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 1-198

    纯化方法

    Antigen affinity

    免疫原

    Human partial recombinant protein (1-198) was used as the immunogen for this p73 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the p73 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the p73 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

    别名

    p73

    背景

    Tumor protein 73(TP73), encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It is mapped to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Furthermore, recent finding are suggesting that over-expression of transcription factors involved in cell cycle regulation and synthesis of DNA in mammalian cells (e.g.: E2F-1) induces the expression of the protein. In addition, p73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate it is markedly increased by gamma-irradiation.

    基因ID

    7161

    途径

    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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