CACYBP 抗体 (Middle Region)
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北京 101111
Quick Overview for CACYBP 抗体 (Middle Region) (ABIN3029276)
抗原
See all CACYBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the middle region of human SIAH Interacting Protein (NTRWDYLTQVEKECKE) was used as the immunogen for this SIP antibody (100% homologous in human, mouse and rat).
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亚型
- IgG
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anti-Calcyclin Binding Protein (CACYBP) (AA 2-228) antibody
CACYBP 适用: 人 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcyclin Binding Protein (CACYBP) (C-Term) antibodyCACYBP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcyclin Binding Protein (CACYBP) (AA 2-228) antibodyCACYBP 适用: 人 WB, ELISA, IF, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcyclin Binding Protein (CACYBP) (AA 1-228) antibodyCACYBP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Calcyclin Binding Protein (CACYBP) (AA 1-228) antibodyCACYBP 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Calcyclin Binding Protein (CACYBP) (AA 1-228) antibodyCACYBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcyclin Binding Protein (CACYBP) antibodyCACYBP 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcyclin Binding Protein (CACYBP) (C-Term) antibodyCACYBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcyclin Binding Protein (CACYBP) (AA 7-47), (N-Term) antibodyCACYBP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ICC, IP, FACS 宿主: 兔 Polyclonal unconjugated
anti-Calcyclin Binding Protein (CACYBP) (AA 160-175), (Middle Region) antibodyCACYBP 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IP, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the SIP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the SIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CACYBP (Calcyclin Binding Protein (CACYBP))
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别名
- SIP
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背景
- CACYBP (Calcyclin-binding protein), also called SIP (SIAH Interacting Protein), is a protein that in humans is encoded by the CACYBP gene. The full-length SIP cDNA encodes a predicted 228-amino acid protein. Sequence analysis of the shortest cDNA derived by 2-hybrid screening revealed an 8-amino acid difference in the deduced open reading frame followed by a stop codon, resulting in a predicted 80-amino acid protein, SIP-short (SIPS). The CACYBP gene is mapped on 1q25.1. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. The C-terminal region of SIP that is homologous to SGT1 was able to complement defects in yeast strains containing SGT1 mutant alleles, demonstrating conservation of SGT1 and SIP protein function.
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UniProt
- Q9HB71
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途径
- Response to Growth Hormone Stimulus
抗原
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