TIMP4 抗体 (AA 208-224)
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Quick Overview for TIMP4 抗体 (AA 208-224) (ABIN3029140)
抗原
See all TIMP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 208-224
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原理
- TIMP4 Antibody
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 208-224 (YRGHLPLRKEFVDIVQP-human) were used as the immunogen for this TIMP4 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the TIMP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the TIMP4 antibody at -20oC.
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- TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))
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别名
- TIMP4
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背景
- The tissue inhibitors of metalloproteinases (TIMPs) inhibit matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. The TIMP4 gene contains 5 exons that span 6 kb of genomic DNA. The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. expressed TIMP4 inhibits MMPs in vitro. TIMP4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2.
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UniProt
- Q99727
抗原
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