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TJP3 抗体 (C-Term)

This anti-TJP3 antibody is a 兔 多克隆 antibody detecting TJP3 in WB 和 IHC (p). Suitable for 大鼠 和 小鼠.
产品编号 ABIN3029137
发货至: 中国

Quick Overview for TJP3 抗体 (C-Term) (ABIN3029137)

抗原

See all TJP3 抗体
TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

适用

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大鼠, 小鼠

宿主

  • 28
  • 2

克隆类型

  • 29
  • 1
多克隆

标记

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This TJP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 9
    • 5
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    • 2
    • 2
    • 1
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    • 1
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    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of mouse Zonula occludens protein 3 (RARDVESSDDEGYDWGPATDL) was used as the immunogen for this ZO-3 antibody (100% rat homology).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the ZO-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the ZO-3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

    别名

    ZO-3

    背景

    TJP3 (Tight junction protein 3), also called ZO-3 (Zona occludens 3), is a protein that in humans is encoded by the TJP3 gene. TJP3/ZO-3 is a member of the family of membrane-associated guanylate kinase-like proteins (MAGUK) that associate with intracellular junctions (Itoh et al., 1999). Haskins et al.(1998) showed that recombinant Tjp3 binds in vitro translated Tjp1 and binds directly to the cytoplasmic tail of occludin but no binding was detected between Tjp3 and Tjp2. Roh et al.(2002) determined that Tjp3 interacted with PATJ(INADL) and that both proteins colocalized to tight junctions in vivo. In vitro studies showed that the sixth and eighth PDZ domains of PATJ mediated interaction with the Tjp3 C-terminal domain and with Cldn1, respectively.

    UniProt

    Q9QXY1
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