MAVS 抗体
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北京 101111
Quick Overview for MAVS 抗体 (ABIN302898)
抗原
See all MAVS 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to a 17 amino acid peptide from near the center of VISA.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide
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anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-65) antibody
MAVS 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 34-96) antibodyMAVS 适用: 人 WB, IHC, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (C-Term) antibodyMAVS 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-540) antibodyMAVS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 150-200) antibodyMAVS 适用: 人 WB, IP, ICC, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 160-450) antibodyMAVS 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal Adri-1 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-30), (N-Term) antibodyMAVS 适用: 小鼠 WB 宿主: 兔 Polyclonal RB42373 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (N-Term) antibodyMAVS 适用: 人, 小鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 146-195) antibodyMAVS 适用: 人, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 470-519) antibodyMAVS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0,5 - 2 μg/mL. Immunohistochemistry: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline, containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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别名
- MAVS
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背景
- Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3, MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK, MIM 600664) and IKKB (IKBKB, MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE, MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1, MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1, MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005).Synonyms: CARD adapter inducing interferon-beta, Cardif, IPS1, Mitochondrial antiviral-signaling protein, Mitochondrial antiviral-signaling protein, Putative NF-kappa-B-activating protein 031N, VISA, Virus-induced-signaling adapter, nterferon-beta promoter stimulator protein 1
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基因ID
- 57506
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NCBI登录号
- NP_065797
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UniProt
- Q7Z434
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途径
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
抗原
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