IER3 抗体 (Center)
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Quick Overview for IER3 抗体 (Center) (ABIN302818)
抗原
See all IER3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- A 24 amino acid peptide near the center of Human IEX1.
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交叉反应 (详细)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide - KLH conjugated corresponding to a 24 amino acid peptide near the center of Human IEX1
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亚型
- IgG
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应用备注
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Western Blot: 2-4 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IER3 (Immediate Early Response 3 (IER3))
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别名
- IER3 / IEX1
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背景
- IEX-1 was originally characterized as a gene induced by ultraviolet radiation and TNF-alpha, which protected human squamous carcinoma cells from apoptosis. Subsequent transfection studies have also shown that expression of IEX-1 in human keratinocytes and mouse fibroblasts results in more rapid proliferation of the cells as compared with controls. The IEX-1 promoter contains binding motifs for both NFKB and p53, suggesting that these proteins may regulate its expression. IEX-1 expression may be modulated by AML1 and TPO.Synonyms: DIF2, Differentiation-dependent gene 2 protein, GLY96, IEX-1, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, PRG1, Radiation-inducible immediate-early gene IEX-1
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基因ID
- 8870
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NCBI登录号
- NP_003888
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UniProt
- P46695
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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