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BCL2A1 抗体

This 兔 多克隆 antibody specifically detects BCL2A1 in WB 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN302791
发货至: 中国
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Quick Overview for BCL2A1 抗体 (ABIN302791)

抗原

See all BCL2A1 抗体
BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

适用

  • 57
  • 32
  • 24
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 55
  • 2
  • 1

克隆类型

  • 37
  • 21
多克隆

标记

  • 26
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
This BCL2A1 antibody is un-conjugated

应用范围

  • 39
  • 22
  • 17
  • 16
  • 8
  • 5
  • 4
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody reacts to 14 amino acid peptide from near the amino terminus of Bfl-1.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Synthetic peptide
  • 应用备注

    Western Blot: 1 - 2 μg/mL. Immunohistochemistry: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline, containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

    背景

    This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.Synonyms: BCL2A1, BCL2L5, BFL1, Bcl-2-like protein 5, Bcl-2-related protein A1, GRS, HBPA1, Hemopoietic-specific early response protein, Protein BFL-1

    基因ID

    597

    NCBI登录号

    NP_004040

    UniProt

    Q16548
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