This mAb reacts with a membrane-associated protein present in normal and malignant neuroendocrine tissues including small cell lung cancer (SCLC). It stains neural and a variable number of endocrine tissues and in the lung it reacts preferentially with SCLC and carcinoids. Its epitope is destroyed during formalin fixation. This antibody was categorized during the First International Workshop on Small Cell Lung Cancer Antigens held in London in April 1987. There are two major types of Lung Carcinoma: non-small cell, which accounts for 80 % of all cases, and small cell, which accounts for roughly 20 % of all lung cancers reported. The lung continues to be a customary place for cancer migration from tumors elsewhere in the body. Treatment depends on the specific cell type of the cancer, level of progression and status of the individual patient.
纯化方法
Protein G affinity chromatography
免疫原
Lung Cancer-associated antigen isolated from small cell lung carcinoma-derived cell line was used as the immunogen for the SCLC Marker antibody.
Optimal dilution of the SCLC Marker antibody should be determined by the researcher.\. Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (Frozen): 0.5-1.0 μg/mL for 30 minutes at RT
限制
仅限研究用
浓度
1 mg/mL
缓冲液
1 mg/mL in 1X PBS, BSA free, sodium azide free
储存液
Azide free
储存条件
4 °C,-20 °C
储存方法
Store the SCLC Marker antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
抗原
Small Cell Lung Cancer (SCLC)
别名
SCLC Marker
背景
This mAb reacts with a membrane-associated protein present in normal and malignant neuroendocrine tissues including small cell lung cancer (SCLC). It stains neural and a variable number of endocrine tissues and in the lung it reacts preferentially with SCLC and carcinoids. Its epitope is destroyed during formalin fixation. This antibody was categorized during the First International Workshop on Small Cell Lung Cancer Antigens held in London in April 1987. There are two major types of Lung Carcinoma: non-small cell, which accounts for 80 % of all cases, and small cell, which accounts for roughly 20 % of all lung cancers reported. The lung continues to be a customary place for cancer migration from tumors elsewhere in the body. Treatment depends on the specific cell type of the cancer, level of progression and status of the individual patient.