CD147 抗体
Quick Overview for CD147 抗体 (ABIN3026723)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
 - This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
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纯化方法
 - Protein G purified CD147 antibody
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免疫原
 - Human T cell line Molt-13 was used as the immunogen for this CD147 antibody.
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亚型
 - IgG1
 
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应用备注
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                        The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD147 antibody to be titered up or down for optimal performance.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Functional Activity: Inhibits homotypic aggregation and adhesion to matrix proteins: order BSA-free antibody format,FACS: 0.5-1 μg/million cells,IF: 1:100-1:200,IHC (FFPE): 1-2 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2) - 
                                            
限制
 - 仅限研究用
 
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浓度
 - 1 mg/mL
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缓冲液
 - 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
 - Azide free
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store the CD147 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
 
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
 - CD147
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背景
 - This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
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基因ID
 - 682
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途径
 - S100 Proteins
 
抗原
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