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Ku70 + Ku80 抗体 (PE)

The 小鼠 单克隆 anti-Ku70 + Ku80 antibody is suitable to detect Ku70 + Ku80 in samples from 人 和 灵长类. It has been validated for FACS 和 IF.
产品编号 ABIN3026514
发货至: 中国
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Quick Overview for Ku70 + Ku80 抗体 (PE) (ABIN3026514)

抗原

Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))

适用

人, 灵长类

宿主

  • 2
  • 1
小鼠

克隆类型

  • 2
  • 1
单克隆

标记

  • 3
This Ku70 + Ku80 antibody is conjugated to PE

应用范围

  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

KU729
  • 无交叉反应

    小鼠, 大鼠, 小鸡

    产品特性

    This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

    纯度

    Protein G affinity chromatography

    免疫原

    Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

    亚型

    IgG1 kappa
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ku70 + Ku80 antibody to be titered up or down for optimal performance.\. Flow Cytometry : 5 μL/test/million cells or 5 μL/test/100 μL of whole blood,Immunofluorescence : 1:50-1:100 for 30 minutes at RT

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    500 μL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the Ku70 + Ku80 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
  • 抗原

    Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))

    别名

    Ku70 + Ku80

    基因ID

    2547
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