SUMO2 抗体
Quick Overview for SUMO2 抗体 (ABIN3026258)
抗原
See all SUMO2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant human protein was used as the immunogen for the SUMO-2 antibody.
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亚型
- IgG1 kappa
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anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibody
SUMO2 适用: 人, 大鼠 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SUMO2-1199 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 63-93) antibodySUMO2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibodySUMO2 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SM23-496 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibodySUMO2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 49-81) antibodySUMO2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-93) antibodySUMO2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal AT10F1 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 63-93), (C-Term) antibodySUMO2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2761 unconjugated
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应用备注
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Optimal dilution of the SUMO-2 antibody should be determined by the researcher.
1. Staining of formalin/paraffin tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the SUMO-2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
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别名
- SUMO-2
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背景
- The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer s disease.
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途径
- Methionine Biosynthetic Process
抗原
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