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PLA2G3 抗体 (Internal Region)

The 兔 多克隆 anti-PLA2G3 antibody is suitable to detect PLA2G3 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN302624
发货至: 中国
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Quick Overview for PLA2G3 抗体 (Internal Region) (ABIN302624)

抗原

See all PLA2G3 抗体
PLA2G3 (Phospholipase A2, Group III (PLA2G3))

适用

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宿主

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克隆类型

  • 25
多克隆

标记

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This PLA2G3 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    特异性

    This antibody detects Group III Secreted Phospholipase A2 (GIII-SPLA2) (PLA2G3) at internal domain.

    纯化方法

    Immunoaffinity chromatography

    免疫原

    Synthetic peptide - KLH conjugated, internal domain of human
  • 应用备注

    Immunohistochemistry on paraffin sections (2.5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原

    PLA2G3 (Phospholipase A2, Group III (PLA2G3))

    别名

    PLA2G3 / sPLA2-III

    背景

    Human group III secreted phospholipase A2 belongs to a superfamily of intracellular and secreted enzymes that catalyze the hydrolysis of glycerophospholipids at the sn-2 position to release fatty acids and lysophospholipids. Group III PLA2 enzymes were originally identified in invertebrates such as bees and scorpions. Human group III sPLA2 has been shown to be a calcium dependent enzyme. It consists of a central group III sPLA2 domain flanked by unique N- and C-terminal domains that are proteolytically removed in most tissues. The sPLA2 domain is sufficient for catalytic activity. SPLA2-III is preferentially expressed in the microvascular endothelium of tissues with inflammation, ischemic injury and cancer.Synonyms: Group 3 secretory phospholipase A2, Group III secretory phospholipase A2, Phosphatidylcholine 2-acylhydrolase GIII

    基因ID

    50487

    NCBI登录号

    NP_056530

    UniProt

    Q9NZ20
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