MYB 抗体 (AA 119-135)
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北京 101111
Quick Overview for MYB 抗体 (AA 119-135) (ABIN3026199)
抗原
See all MYB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 119-135
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.
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亚型
- IgG1 kappa
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应用备注
- The optimal dilution of the c-Myb antibody for each application should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence (1-2 μg/mL)
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the c-Myb antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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别名
- C-Myb
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背景
- The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
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途径
- Chromatin Binding, Positive Regulation of Immune Effector Process
抗原
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