GNRHR 抗体 (AA 1-29)
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- 抗原 See all GNRHR 抗体
- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
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抗原表位
- AA 1-29
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适用
- 人, 大鼠, 兔
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GNRHR antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Protein G affinity chromatography
- 免疫原
- A synthetic peptide aa 1-29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) from the N-terminal of human GnRHR was used as the immunogen for the GnRH Receptor antibody.
- 克隆位点
- F1G4 or GNRH03
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product GNRHR Primary Antibody
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anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (AA 201-328) antibody
GNRHR 适用: 人, 大鼠 WB, ELISA, IHC (p), IHC (fro), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) antibodyGNRHR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) antibodyGNRHR 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (N-Term) antibodyGNRHR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (Internal Region) antibodyVerified GNRHR 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (AA 3-13), (Extracellular), (N-Term) antibodyGNRHR 适用: 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Optimal dilution of the GnRH Receptor antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1),Prediluted format : incubate for 30 min at RT (2) - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the GnRH Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- 抗原
- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
- 别名
- GnRH Receptor (GNRHR 产品)
- 背景
- Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.
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