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CD16 抗体

This anti-CD16 antibody is a 小鼠 单克隆 antibody detecting CD16 in FACS, IF 和 Func. Suitable for 人.
产品编号 ABIN3025888
发货至: 中国

Quick Overview for CD16 抗体 (ABIN3025888)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

HuNK2
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    Human peripheral blood lymphocytes from a NK-leukemia patient were used as the immunogen for the CD16 antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal dilution of the CD16 antibody should be determined by the researcher.\. Functional Activity (Order SAF formulation),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the CD16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    CD16

    别名

    CD16

    背景

    Recognizes a protein of 50-65  kDa, identified as CD16 (Workshop IV, Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This mAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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