IFNA2 抗体
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北京 101111
Quick Overview for IFNA2 抗体 (ABIN3025780)
抗原
See all IFNA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- Purified recombinant human IFNA2 was used as the immunogen for the Interferon alpha 2 antibody.
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亚型
- IgG kappa
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应用备注
- Optimal dilution of the Interferon alpha 2 antibody should be determined by the researcher.\. ELISA: order BSA/azide-free format for coating
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Interferon alpha 2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- IFNA2 (Interferon, alpha 2 (IFNA2))
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别名
- Interferon alpha 2
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背景
- Recognizes a protein of 16-27 kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This mAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this mAb is called "site I" and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
抗原
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