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CD22 抗体

This 小鼠 单克隆 antibody specifically detects CD22 in FACS, IF 和 Func. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN3025757
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD22 抗体 (ABIN3025757)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

  • 228
  • 65
  • 25
  • 5
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 139
  • 100
  • 16
  • 13
小鼠

克隆类型

  • 206
  • 60
  • 1
单克隆

标记

  • 121
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  • 10
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD22 antibody is un-conjugated

应用范围

  • 169
  • 115
  • 77
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  • 43
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  • 27
  • 17
  • 14
  • 11
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  • 5
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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

MYG13
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    Human Raji cells were used as the immunogen for the CD22 antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal dilution of the CD22 antibody should be determined by the researcher.\. Functional Activity (Order SAF formulation),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the CD22 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    CD22

    背景

    Recognizes a protein of 130-140  kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
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