VCAM1 抗体
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北京 101111
Quick Overview for VCAM1 抗体 (ABIN3025723)
抗原
See all VCAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- Activated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM1 antibody.
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亚型
- IgG1 kappa
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应用备注
- Optimal dilution of the VCAM1 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL, Functional blocking: order BSA/azide free format
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the VCAM1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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别名
- VCAM1
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背景
- Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. L1CAM serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This mAb inhibits the binding of leukocytes to L1CAM on stimulated endothelial cells.
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途径
- Carbohydrate Homeostasis
抗原
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