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VCAM1 抗体

The 小鼠 单克隆 anti-VCAM1 antibody (Clone B-K9) (ABIN3025723) specifically detects VCAM1 in FACS, IF 和 BP. The antibody is reactive with 人 samples.
产品编号 ABIN3025723
发货至: 中国
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Quick Overview for VCAM1 抗体 (ABIN3025723)

抗原

See all VCAM1 抗体
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This VCAM1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Peptide (BP)

克隆位点

B-K9
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    Activated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM1 antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal dilution of the VCAM1 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL, Functional blocking: order BSA/azide free format

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the VCAM1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    别名

    VCAM1

    背景

    Recognizes a protein of 110  kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. L1CAM serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This mAb inhibits the binding of leukocytes to L1CAM on stimulated endothelial cells.

    途径

    Carbohydrate Homeostasis
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