TYR 抗体
Our Local Distributor
北京 101111
Quick Overview for TYR 抗体 (ABIN3025624)
抗原
See all TYR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- TYR Antibody Cocktail (Tyrosinase)
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Recombinant human protein was used as the immunogen for the TYR antibody cocktail.
-
亚型
- IgG2a, kappa
-
-
anti-Tyrosinase (TYR) (AA 1-377) antibody
TYR 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A2-F4 unconjugated
anti-Tyrosinase (TYR) (AA 20-340) antibodyTYR 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (AA 486-513) antibodyTYR 适用: 人 IHC, WB, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (AA 1-377) antibodyTYR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) antibodyTYR 适用: 人, 小鼠, 猴 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (AA 486-513), (C-Term) antibodyTYR 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19155 unconjugated
anti-Tyrosinase (TYR) (C-Term) antibodyTYR 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) antibodyTYR 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal T311 unconjugated
anti-Tyrosinase (TYR) (AA 176-205) antibodyTYR 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB19154 unconjugated
anti-Tyrosinase (TYR) (C-Term) antibodyTYR 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Optimal dilution of the TYR antibody cocktail should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the TYR antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- TYR (Tyrosinase (TYR))
-
别名
- TYR
-
背景
- Recognizes a cluster of proteins between 70-80 kDa, identified as Tyrosinase/TYR. Occasionally a minor band at 55 kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.
-
UniProt
- P14679
抗原
-
