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ACTH 抗体 (AA 1-24)

ACTH 适用: 人, 大鼠, 小鼠 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal AH26 unconjugated
产品编号 ABIN3025414
发货至: 中国
  • 抗原 See all ACTH 抗体
    ACTH (Adrenocorticotropic hormone (ACTH))
    抗原表位
    • 34
    • 32
    • 19
    • 15
    • 14
    • 8
    • 2
    • 2
    AA 1-24
    适用
    • 115
    • 80
    • 46
    • 3
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 80
    • 52
    小鼠
    克隆类型
    • 80
    • 52
    单克隆
    标记
    • 48
    • 12
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This ACTH antibody is un-conjugated
    应用范围
    • 70
    • 68
    • 67
    • 66
    • 35
    • 32
    • 25
    • 25
    • 23
    • 18
    • 11
    • 10
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    A synthetic peptide corresponding to aa 1-24 of human ACTH was used as the immunogen for this ACTH antibody.
    克隆位点
    AH26
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ACTH Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the ACTH antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    Store the ACTH antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    ACTH (Adrenocorticotropic hormone (ACTH))
    别名
    ACTH / Synacthen (ACTH 产品)
    别名
    ACTH antibody, BE antibody, Beta-LPH antibody, Clip antibody, Gamma-LPH antibody, Npp antibody, Pomc-1 antibody, Pomc1 antibody, alpha-MSH antibody, alphaMSH antibody, beta-MSH antibody, gamma-MSH antibody, CLIP antibody, LPH antibody, MSH antibody, NPP antibody, POC antibody, pro-opiomelanocortin-alpha antibody, proopiomelanocortin antibody, Pomc antibody, POMC antibody
    物质类
    Hormone
    背景
    POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific post-translational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH (also called Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. Clone AH26 antibody is specific to Synacthen (aa 1-24 of ACTH) and does not react with CLIP (aa 17-39). ACTH is produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Specific antibody is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) that cause paraneoplastic syndromes by secreting ACTH.
    基因ID
    5443
    途径
    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
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