PAX6 抗体
Quick Overview for PAX6 抗体 (ABIN3025378)
抗原
See all PAX6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Protein G purified antibody
-
免疫原
- Recombinant human PAX6 protein was used as the immunogen for this antibody.
-
亚型
- IgG1 kappa
-
-
anti-Paired Box 6 (PAX6) (AA 1-122) antibody
PAX6 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 1F6G2 unconjugated
anti-Paired Box 6 (PAX6) (AA 51-150) antibodyPAX6 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 183-210) antibodyPAX6 适用: 人 WB, IF, ELISA, FACS, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 195-233), (Middle Region) antibodyPAX6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15517 unconjugated
anti-Paired Box 6 (PAX6) (AA 1-300) antibodyPAX6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) antibodyPAX6 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-706M unconjugated
-
-
应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the PAX6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
-
-
- PAX6 (Paired Box 6 (PAX6))
-
别名
- PAX6
-
背景
- PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
-
基因ID
- 5080
-
途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
-
