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PTH 抗体 (C-Term)

The 小鼠 单克隆 anti-PTH antibody is suitable to detect PTH in samples from 人. It has been validated for IF 和 IHC (p).
产品编号 ABIN3025368
发货至: 中国
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Room 801-803
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Quick Overview for PTH 抗体 (C-Term) (ABIN3025368)

抗原

See all PTH 抗体
PTH (Parathyroid Hormone (PTH))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PTH antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PRTM1-3
  • 抗原表位

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    C-Term

    纯化方法

    Protein G affinity chromatography

    免疫原

    A C-terminal partial recombinant protein from the human protein was used as the immunogen for the Parathyroid Hormone antibody.

    亚型

    IgG2b kappa
  • 应用备注

    Titering of the Parathyroid Hormone antibody may be required for optimal performance.

    1. FFPE testing requires sections to be boiled in  pH 6 10  mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Parathyroid Hormone antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    PTH (Parathyroid Hormone (PTH))

    别名

    Parathyroid Hormone

    物质类

    Hormone

    背景

    Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide containing 84 amino acids, yet effective hormone-receptor interaction requires solely the 34-N-terminal amino acids. While PTH acts to increase the concentration of ionic calcium (Ca2+) in the blood, calcitonin, a hormone produced by the parafollicular cells (C cells) of the thyroid gland, acts to decrease ionic calcium concentration. PTH essentially acts to increase the concentration of calcium in the blood by acting upon the parathyroid hormone 1 receptor, which is present at high levels in bone and kidney, and the parathyroid hormone 2 receptor, which is present at high levels in the central nervous system, pancreas, testis, and placenta. [Wiki]

    途径

    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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