PDE1C 抗体 (C-Term)
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Quick Overview for PDE1C 抗体 (C-Term) (ABIN302536)
抗原
See all PDE1C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Phosphodiesterase 1C (PDE1C) at C-terminal domain. Mouse and Rat.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- PDE1C antibody was raised against synthetic peptide from C-terminal domain of human PDE1C.
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anti-phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (AA 375-409) antibody
PDE1C 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB53462 unconjugated
anti-phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (AA 542-634) antibodyPDE1C 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (AA 431-480) antibodyPDE1C 适用: 人, 小鼠, 大鼠, Cow, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (N-Term) antibodyPDE1C 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on paraffin sections (5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.21 mg/mL
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缓冲液
- PBS containing 0.09 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
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别名
- PDE1C
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背景
- Phosphodiesterase 1C is a cAMP/cGMP dual-specific, calcium/calmodullin-dependent phosphodiesterase. PDE1C has been shown to affect vascular smooth muscle proliferation and atherosclerosis, insulin secretion regulation, spermatozoa development, and erectile dysfunction. At least five PDE1C isoforms have been reported, the expression of which are regulated in a tissue/cell-specific manner.Synonyms: 5'-cyclic nucleotide phosphodiesterase 1C, Calcium/calmodulin-dependent 3', Cam-PDE 1C, HCAM3, Phosphodiesterase 1C, Phosphodiesterase-1C calmodulin-dependent, hCam-3
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基因ID
- 5137
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NCBI登录号
- NP_001177985
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UniProt
- Q14123
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
抗原
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