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Myogenin 抗体 (full length)

The 小鼠 单克隆 anti-Myogenin antibody is suitable to detect Myogenin in samples from 人, 小鼠 和 大鼠. It has been validated for IHC (p).
产品编号 ABIN3025314
发货至: 中国
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Quick Overview for Myogenin 抗体 (full length) (ABIN3025314)

抗原

See all Myogenin (MYOG) 抗体
Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))

适用

  • 140
  • 95
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  • 28
  • 15
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  • 2
人, 小鼠, 大鼠

宿主

  • 78
  • 75
  • 1
小鼠

克隆类型

  • 92
  • 62
单克隆

标记

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  • 9
  • 7
  • 6
  • 4
  • 4
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Myogenin antibody is un-conjugated

应用范围

  • 101
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  • 63
  • 39
  • 31
  • 19
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  • 11
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  • 7
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

MGN185-F5D
  • 抗原表位

    • 29
    • 16
    • 14
    • 13
    • 10
    • 8
    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-224, full length

    原理

    Myogenin Antibody Cocktail (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    Full length human recombinant protein (MGN185) and a partial rat recombinant protein (amino acid 30-224) (F5D) were used as the immunogens for this Myogenin antibody cocktail.

    亚型

    IgG1, kappa
  • 应用备注

    The optimal dilution of the Myogenin antibody for each application should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Myogenin antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))

    别名

    Myogenin

    背景

    Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80 % amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms tumor.

    UniProt

    P15173

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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