MVP 抗体
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北京 101111
Quick Overview for MVP 抗体 (ABIN3025305)
抗原
See all MVP 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Major Vault Protein Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Proteins precipitated from human breast cancer MCF-7 cells were used as the immunogen for the Major Vault Protein antibody.
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亚型
- IgG1, kappa
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应用备注
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Optimal dilution of the Major Vault Protein antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Major Vault Protein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MVP (Major Vault Protein (MVP))
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别名
- Major Vault Protein
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背景
- MVP is required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
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UniProt
- Q14764
抗原
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