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PDE9A 抗体

PDE9A 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN302526
发货至: 中国
  • 抗原 See all PDE9A 抗体
    PDE9A (phosphodiesterase 9A (PDE9A))
    适用
    • 24
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 20
    • 4
    克隆类型
    • 22
    • 2
    多克隆
    标记
    • 18
    • 3
    • 2
    • 1
    This PDE9A antibody is un-conjugated
    应用范围
    • 17
    • 12
    • 11
    • 7
    • 5
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    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects Phosphodiesterase 9A (PDE9A) at internal domain.
    纯化方法
    Immunoaffinity chromatography
    免疫原
    PDE9A antibody was raised against synthetic peptide from human PDE9A.
    Top Product
    Discover our top product PDE9A Primary Antibody
  • 应用备注
    Immunohistochemistry on paraffin sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原
    PDE9A (phosphodiesterase 9A (PDE9A))
    别名
    PDE9A (PDE9A 产品)
    别名
    PDE9A antibody, MGC116558 antibody, Pde9a antibody, HSPDE9A2 antibody, PDE9A1 antibody, phosphodiesterase 9A antibody, phosphodiesterase 9A S homeolog antibody, high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A antibody, PDE9A antibody, pde9a.S antibody, Pde9a antibody, LOC100549810 antibody, pde9a antibody
    背景
    Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.Synonyms: 5'-cyclic phosphodiesterase 9A, HSPDE9A2, High affinity cGMP-specific 3', Phosphodiesterase 9A, Phosphodiesterase PDE9A21
    基因ID
    5152
    NCBI登录号
    NP_001001567
    UniProt
    O76083
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