PDE8B 抗体 (Internal Region)
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Quick Overview for PDE8B 抗体 (Internal Region) (ABIN302525)
抗原
See all PDE8B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody detects Phosphodiesterase 8B (PDE8B) at internal domain.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- PDE8B antibody was raised against synthetic peptide from internal domain of human PDE8B.
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anti-phosphodiesterase 8B (PDE8B) (Internal Region) antibody
PDE8B 适用: 人, 马, 猴, Bat IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8B (PDE8B) (AA 296-324) antibodyPDE8B 适用: 小鼠 WB 宿主: 兔 Polyclonal RB42219 unconjugated
anti-phosphodiesterase 8B (PDE8B) (AA 18-110) antibodyPDE8B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on paraffin sections (5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,3 mg/mL
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缓冲液
- PBS containing 0.09 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- PDE8B (phosphodiesterase 8B (PDE8B))
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别名
- PDE8B
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背景
- Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.Synonyms: 5'-cyclic phosphodiesterase 8B, ADSD, Cell proliferation-inducing gene 22 protein, High affinity cAMP-specific and IBMX-insensitive 3', PIG22, PPNAD3, Phosphodiesterase 8B, hsPDE8B
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基因ID
- 8622
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NCBI登录号
- NP_001025022
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UniProt
- O95263
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
抗原
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