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PDE8B 抗体 (Internal Region)

PDE8B 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN302525
发货至: 中国
  • 抗原 See all PDE8B 抗体
    PDE8B (phosphodiesterase 8B (PDE8B))
    抗原表位
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Internal Region
    适用
    • 15
    • 11
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 21
    克隆类型
    • 21
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    This PDE8B antibody is un-conjugated
    应用范围
    • 13
    • 10
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects Phosphodiesterase 8B (PDE8B) at internal domain.
    纯化方法
    Immunoaffinity chromatography
    免疫原
    PDE8B antibody was raised against synthetic peptide from internal domain of human PDE8B.
    Top Product
    Discover our top product PDE8B Primary Antibody
  • 应用备注
    Immunohistochemistry on paraffin sections (5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,3 mg/mL
    缓冲液
    PBS containing 0.09 % sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原
    PDE8B (phosphodiesterase 8B (PDE8B))
    别名
    PDE8B (PDE8B 产品)
    别名
    PDE8B antibody, ADSD antibody, PPNAD3 antibody, B230331L10Rik antibody, C030047E14Rik antibody, RNPDE8B antibody, phosphodiesterase 8B antibody, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antibody, PDE8B antibody, LOC100468338 antibody, pde8b antibody, Pde8b antibody
    背景
    Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.Synonyms: 5'-cyclic phosphodiesterase 8B, ADSD, Cell proliferation-inducing gene 22 protein, High affinity cAMP-specific and IBMX-insensitive 3', PIG22, PPNAD3, Phosphodiesterase 8B, hsPDE8B
    基因ID
    8622
    NCBI登录号
    NP_001025022
    UniProt
    O95263
    途径
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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