PDE8A 抗体 (N-Term)
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Quick Overview for PDE8A 抗体 (N-Term) (ABIN302523)
抗原
See all PDE8A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Phosphodiesterase 8A (PDE8A) near N-terminus.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- PDE8A antibody was raised against synthetic peptide from near N-terminus of human PDE8A.
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应用备注
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Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- PDE8A (phosphodiesterase 8A (PDE8A))
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别名
- PDE8A
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背景
- Phosphodiesterase 8A, a high affinity, cAMP-specific phosphodiesterase, has been implicated in penile erectile dysfunction. PDE8A activity is inhibited by dipyridamole, but not by rolipram, zaprinast, or IBMX. At least five splice variants and four protein isoforms have been reported.Synonyms: 5'-cyclic phosphodiesterase 8A, FLJ16150, High affinity cAMP-specific and IBMX-insensitive 3', HsT19550, Phosphodiesterase 8A, cAMP-specific cyclic nucleotide phosphodiesterase 8A
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基因ID
- 5151
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NCBI登录号
- NP_002596
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UniProt
- O60658
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途径
- cAMP Metabolic Process
抗原
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