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LSD1 抗体 (N-Term)

Name: LSD1 抗体 (N-Term)
SKU: ABIN3025191
Availability: OutOfStock

KDM1A 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot testing of human samples with LSD1 / KDM1 antibody at 0. (LSD1 抗体 (N-Term))

Western blot testing of mouse samples with LSD1 / KDM1 antibody at 0. (LSD1 抗体 (N-Term))

IHC testing of FFPE human testis tissue with LSD1 antibody at 5ug/ml. (LSD1 抗体 (N-Term))

IHC

IHC testing of FFPE human breast tissue with LSD1 antibody at 5ug/ml. (LSD1 抗体 (N-Term))

IHC

4 images

产品编号 ABIN3025191

发货至: 中国

Datasheet as PDF

抗原 See all LSD1 (KDM1A) 抗体

LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
抗原表位
15

8

7

6

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
N-Term
适用
78

37

29

6

3

2

1

1

1

1

1

1

1
人, 小鼠
宿主
61

16

1

1
兔
Compatible Secondaries
克隆类型
62

18
多克隆
标记
60

3

3

3

1

1

1

1

1

1

1

1

1

1

1
This LSD1 antibody is un-conjugated
应用范围
72

36

26

22

19

13

13

12

6

5

4

4

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

Protein A affinity chromatography

免疫原

A recombinant protein fragment from the N-terminal region of human LSD1 / KDM1 was used as the immunogen for this antibody.

亚型

IgG

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anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 130-380) antibody
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anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 709-876) antibody
KDM1A 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1H2F8 unconjugated

anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 55-263) antibody
KDM1A 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3F9D2 unconjugated

anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 55-263) antibody
KDM1A 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3F9A3 unconjugated

anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 753-851) antibody
KDM1A 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E7 unconjugated

anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 108-142) antibody
KDM1A 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 819-852) antibody
KDM1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 819-852), (C-Term) antibody
KDM1A 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7583 unconjugated

anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 100-150) antibody
KDM1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Provided assay concentrations are suggestions only, LSD1 / KDM1 antibody titration may be required for optimal results.\. Western blot: 0.5-2 μg/mL, IHC (FFPE): 5 μg/mL

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the LSD1 / KDM1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

别名

LSD1 / KDM1 (KDM1A 产品)

别名

AOF2 antibody, BHC110 antibody, KDM1 antibody, LSD1 antibody, 1810043O07Rik antibody, AA408884 antibody, Aof2 antibody, D4Ertd478e antibody, Kdm1 antibody, Lsd1 antibody, mKIAA0601 antibody, DKFZp459N2450 antibody, RGD1562975 antibody, aof2 antibody, kdm1 antibody, wu:fb82e06 antibody, wu:fc51a02 antibody, wu:fj36a05 antibody, wu:fj66b06 antibody, KDM1A antibody, lsd1 antibody, xLSD1 antibody, AtLSD1 antibody, F9F13.30 antibody, F9F13_30 antibody, LESION SIMULATING DISEASE antibody, LESION SIMULATING DISEASE 1 antibody, lysine demethylase 1A antibody, lysine (K)-specific demethylase 1A antibody, lysine (K)-specific demethylase 1a antibody, LSD1 zinc finger family protein antibody, KDM1A antibody, Kdm1a antibody, kdm1a antibody, LSD1 antibody

背景

LSD1 (Lysine-specific demethylase 1), also called KDM1 (lysine (K)-specific demethylase 1A), is the first histone demethylase to be identified and regulates transcription via demethylation of lysines 4 and 9 of Histone H3. It negatively regulates pro-inflammatory cytokine expression by interacting with the genes promoter region. It also plays a role in tumor development where overexpression of LSD1 correlates with a poor prognosis. It is upregulated in cancers of the bladder, breast, lung, colon, and GI tract as well as neuroblastoma and cells of mesenchymal origin such as chondrosarcoma, osteosarcoma, rhabdomyosarcoma and Ewing's sarcoma (Bennani-Baiti et al, 2012).

基因ID

23028

途径

Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect