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FLI1 抗体 (AA 107-216)

FLI1 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal FLVI1-1 unconjugated
产品编号 ABIN3024862
发货至: 中国
  • 抗原 See all FLI1 抗体
    FLI1 (Friend Leukemia Virus Integration 1 (FLI1))
    抗原表位
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-216
    适用
    • 70
    • 25
    • 19
    • 9
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    宿主
    • 48
    • 20
    • 2
    小鼠
    克隆类型
    • 48
    • 22
    单克隆
    标记
    • 49
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLI1 antibody is un-conjugated
    应用范围
    • 58
    • 29
    • 25
    • 17
    • 15
    • 10
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Human partial recombinant protein (amino acids 107-216) was used as the immunogen for this FLI1 antibody.
    克隆位点
    FLVI1-1
    亚型
    IgG
    Top Product
    Discover our top product FLI1 Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FLI1 antibody to be titered up or down for optimal performance.\. Western blot: 1-2 μg/m,l,FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the FLI1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    FLI1 (Friend Leukemia Virus Integration 1 (FLI1))
    别名
    FLI1 (FLI1 产品)
    背景
    Friend leukemia integration 1 is a member of the ETS family of DNA binding transcription factors that is involved in cellular proliferation and tumorigenesis. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing's Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi's Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.
    基因ID
    2313
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