PTH 抗体 (AA 32-115)
Quick Overview for PTH 抗体 (AA 32-115) (ABIN3024771)
抗原
See all PTH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 32-115
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产品特性
- Epitope of this mAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 32-115 of human PTH was used as the immunogen for the Parathyroid Hormone antibody.
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亚型
- IgG2b kappa
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anti-Parathyroid Hormone (PTH) antibody
PTH 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, StM 宿主: 兔 Monoclonal PTH-2295R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-525R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Parathyroid Hormone (PTH) antibodyPTH 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal 105G7 unconjugated
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC, StM 宿主: 兔 Monoclonal PTH-1717R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rPTH-911 unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 71-115) antibodyPTH 适用: 人 IHC, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Optimal dilution of the Parathyroid Hormone antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Parathyroid Hormone antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- PTH (Parathyroid Hormone (PTH))
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别名
- Parathyroid Hormone
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物质类
- Hormone
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背景
- Epitope of this mAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
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途径
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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