CD147 抗体
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北京 101111
Quick Overview for CD147 抗体 (ABIN3024283)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- PEG precipitation
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免疫原
- Native human leukocytes were used as the immunogen for the Emmprin antibody.
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亚型
- IgM
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应用备注
- Optimal dilution of the Emmprin antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Emmprin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
- Emmprin
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背景
- CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
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途径
- S100 Proteins
抗原
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