CD147 抗体 (Extracellular)
Our Local Distributor
北京 101111
Quick Overview for CD147 抗体 (Extracellular) (ABIN3024197)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- Extracellular
-
原理
- CD147 Antibody (azide and preservative free)
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Recombinant human protein was used as the immunogen for the CD147 antibody. The epitope is known to be extracellular.
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
-
Titering of the CD147 antibody may be required for optimal performance.
1. FFPE testing requires sections to be boiled in pH 6 10 mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the CD147 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
-
别名
- CD147
-
背景
- Basigin (BSG) also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the BSG gene. This protein is a determinant for the Ok blood group system. Basigin has been shown to be an essential receptor on red blood cells for the human malaria parasite, Plasmodium falciparum. It has a variety of functions. In addition to its metalloproteinase-inducing ability, basigin also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. CD147 is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes. [Wiki]
-
UniProt
- P35613
-
途径
- S100 Proteins
抗原
-