CD147 抗体 (Extracellular Domain)
Quick Overview for CD147 抗体 (Extracellular Domain) (ABIN3024197)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - Extracellular Domain
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纯化方法
 - Protein G affinity chromatography
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免疫原
 - Recombinant human protein was used as the immunogen for the CD147 antibody. The epitope is known to be extracellular.
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亚型
 - IgG1
 
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应用备注
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                        Titering of the CD147 antibody may be required for optimal performance.
1. FFPE testing requires sections to be boiled in pH 6 10 mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2) - 
                                            
限制
 - 仅限研究用
 
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浓度
 - 1 mg/mL
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缓冲液
 - 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
 - Azide free
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store the CD147 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
 
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
 - CD147
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背景
 - Basigin (BSG) also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the BSG gene. This protein is a determinant for the Ok blood group system. Basigin has been shown to be an essential receptor on red blood cells for the human malaria parasite, Plasmodium falciparum. It has a variety of functions. In addition to its metalloproteinase-inducing ability, basigin also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. CD147 is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes. [Wiki]
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途径
 - S100 Proteins
 
抗原
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